MedPath

Detection of COVID-19 in Saliva Collection

Completed
Conditions
Saliva Collection
RT-PCR
Nasopharyngeal Sample
Sars-CoV2
Registration Number
NCT04386551
Lead Sponsor
Centre Hospitalier Universitaire, Amiens
Brief Summary

Since December 2019, the world has faced a pandemic of COVID-19, an infectious disease caused by SARS-CoV-2, a virus that emerged in China. The reference diagnosis is based on the search for the SARS-COV-2 genome in the nasopharyngeal sample.

Carrying out this sample requires the competence of a healthcare professional and presents some inconveniences for the tested patient. Because saliva collection is simple, non-invasive, painless and inexpensive, and can be performed by poorly trained personnel, it could be an alternative to the reference nasopharyngeal sample. SARS-CoV2 detection in human saliva could be a potential diagnosis of COVID infection.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
501
Inclusion Criteria
  • patient hospitalized at the Amiens CHU in a COVID-19 unit
  • patient seen as outpatient in the area of infectious pathologies for COVID-19 infection
Exclusion Criteria
  • Patients under 18
  • patients under guardianship or curators

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Detection of SARS-CoV-2 RNA in the saliva sampleday 1

Detection of SARS-CoV-2 RNA in the saliva sample

Concordance between the Saliva sample and the nasonasopharyngeal sample SARS-CoV-2 RT-PCR resultsday 1

Concordance between the Saliva sample and the nasonasopharyngeal sample SARS-CoV-2 RT-PCR results

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

CHU Amiens

🇫🇷

Amiens, France

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