Evaluating the efficacy and safety of rivaroxaban comparing to warfarin in patients with chronic thromboembolic pulmonary hypertension (CTEPH) following endartrectomy surgery

Phase 2

Recruiting

• Conditions: Chronic Thrombo Embolic Pulmonary Hypertension(CTEPH).; Chronic Thromboembolic Pulmonary Hypertension.; I27. 24

• Registration Number: IRCT20151227025726N22
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 November 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

Patients undergoing endarterectomy following chronic thromboembolic pulmonary hypertension at Masih Daneshvari Hospital.

Exclusion Criteria

Any allergies to the prescribed medication
Any bleeding includes active gastrointestinal, pulmonary, genitourinary bleeding
Cerebral aneurysm
Intracranial bleeding
Aneurysm and aortic dissection
A patient undergoing spinal puncture
Blood dyscrasia
Uncontrolled blood pressure (110/180 mmHg Inflammation and pericardial effusion
Bacterial endocarditis
Pregnancy and lactation
Liver disease(child pugh B&C)
GFR<30 mL/min
Any coagulation disorder
If the patient has been prescribed strong Cyp450 and Pgp inhibitors such as ketoconazole, itraconazole, posaconazole and ritonavir.

Study & Design

• Study Type: interventional
• Study Design: Not specified