Aspirin Prescription For Moderate- and High-Risk Obstetric Population in Outpatient Clnic; A Quality Improvement Project.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Aspirin prescription
研究概览
简要总结
Ρrееςlаmpѕia is a syndrome characterised by the new onset of hуреrtеnѕion plus proteinuria, end-organ dysfunction, or both after 20 weeks of gestation. It complicates 3-5% of pregnancies.
Low-dose aspirin reduces the frequency of рrееςlampsia, as well as related adverse рrеgոaոcy outcomes (preterm birth, growth restriction), by 10 to 70% when taken by patients аt moderate to high risk of the disease. It has an excellent maternal/fetal safety profile. Thus, it is a reasonable preventive strategy for these patients.
A pilot study at our hospital found that not all patients who are candidates for aspirin prescription receive it (only 40%). This audit cycle aims to increase aspirin prescription rates for moderate and high-risk obstetric populations.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women at high risk are those with any of the following:
- •hypertensive disease during a previous pregnancy
- •chronic kidney disease
- •autoimmune disease such as systemic lupus erythematosus or antiphospholipid syndrome
- •type 1 or type 2 diabetes
- •chronic hypertension.
- •Women with more than one moderate risk factor, such as are:
- •nulliparity
- •age 40 years or older
- •pregnancy interval of more than 10 years
- •body mass index (BMI) of 35 kg/m2 or more at first visit
- •family history of pre-eclampsia
- •multi-fetal pregnancy.
排除标准
- •None. All eligible candidates will be included.
研究组 & 干预措施
Obstetric population candidate for aspirin prescription
Moderate- and high-risk obstetric population
干预措施: Aspirin prescription on outpatient basis (Other)
结局指标
主要结局
Aspirin prescription
时间窗: Six months
次要结局
未报告次要终点