Prevalence and Impact of Diabetes Mellitus in Hospitalized COVID-19 Patients in a Tunisian Center: a Cross Sectional Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Prevalence
- Sponsor
- Sana Rouis
- Enrollment
- 866
- Locations
- 1
- Primary Endpoint
- Admission to Intensive Care Units
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Objective: The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19.
Methods: Data of laboratory-confirmed hospitalized patients at the COVID-19 unit of Ibn El Jazzar University Hospital in Kairouan between September 2020 and August 2021 were analysed, in a cross-sectional study. The population was classified into two groups (COVID-19 patients with versus without diabetes). Primary outcomes were the overall length of hospital stay, the admission to the intensive care unit (ICU), and death.
Detailed Description
The outbreak of the coronavirus disease 2019 (Covid-19) has become an evolving worldwide health crisis. With the rising prevalence of diabetes mellitus has come an increasing awareness of their impacts on infectious diseases, and the risk for post-infection complications and mortality from critical infections. Objective: The objective of this study was to evaluate the prevalence and impact of diabetes mellitus on the severity and mortality of COVID-19. Methods: Data of laboratory-confirmed hospitalized patients at the COVID-19 unit of Ibn El Jazzar University Hospital in Kairouan between September 2020 and August 2021 were analysed, in a cross-sectional study. The population was classified into two groups (COVID-19 patients with versus without diabetes). Primary outcomes were the overall length of hospital stay, the admission to the intensive care unit (ICU), and death. Association between diabetes and death was assessed in a Cox proportional hazards model.
Investigators
Sana Rouis
Assistant professor in Infectious Diseases
Faculty of Medicine, Sousse
Eligibility Criteria
Inclusion Criteria
- •Confirmed cases indicated the patients whose real-time reverse transcriptase-polymerase chain reaction (RT-PCR) analysis results for nasal swab specimens were positive.
Exclusion Criteria
- •the investigators didn't included patients who were suspected cases, and whose the result of PCR test was negative ; Covid-19 patients admitted in other departments (Cardiology, pediatrics, obstetrics, intensive care unit, medicine, surgery department...) ; and patients with missing medical records. -
Outcomes
Primary Outcomes
Admission to Intensive Care Units
Time Frame: 7 days
patients who were transferred to ICU
death
Time Frame: 7 days
patients who were dead
overall length of hospital stay
Time Frame: 7 days
length of hospital stay from admission to discharge (or transfer or death)