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Clinical Trials/NCT07473141
NCT07473141
Not yet recruiting
Not Applicable

Quantification of Gait Differences Between Healthy Volunteers and Patients Suffering From Gait Disorders Through Wearable Sensors

IRCCS San Raffaele1 site in 1 country100 target enrollmentStarted: March 2, 2026Last updated:
InterventionsGait assessment

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
100
Locations
1
Primary Endpoint
Mean differences in joint range of motion expressed in degrees of movement (hip, knee, ankle) measured by sensors (Inertial Measurement Units) between patients and healthy volunteers

Overview

Brief Summary

This is a single-centre, cross-sectional observational study with adjunctive procedure for the healthy voluteers at IRCCS Ospedale San Raffaele's Rehabilitation Department.

Patients (n=50): use of inertial measurement units (IMU) and electromyographic (EMG) data routinely acquired during their standard clinical gait-rehabilitation sessions (no protocol changes; purely observational, data extracted from treatments).

Healthy volunteers (n=50): age- and sex-matched volunteers who complete three 18 meters gait sessions with IMUs on trunk, thighs, shanks and feet and surface EMG on gluteus, quadriceps, hamstrings, tibialis anterior, and gastrocnemius. Healthy volunteers will be enrolled from hospital personnel, family members of the patients in visit at San Raffaele Hospital.

Data & Analysis: Kinematic (range of motion - ROM, step timing, walking speed) and EMG (activation amplitude/timing) parameters will be extracted. Between-group comparisons will employ t-tests/analysis of variance - ANOVA - (or non-parametric equivalents).

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Hospitalized at the Department of Rehabilitation and Functional Recovery of IRCCS Ospedale San Raffaele - Milan (during the hospitalization period)
  • Ability to understand and sign informed consent
  • ≥ 18 years ≤80 years
  • Male and female
  • Presence of clinically diagnosed gait impairments
  • No skin conditions or allergies preventing sensor application

Exclusion Criteria

  • Cognitive impairment interfering with task comprehension
  • Cardiorespiratory instability or other contraindications to walking assessment

Arms & Interventions

Patients

Intervention: Gait assessment (Other)

Healthy volunteers

Intervention: Gait assessment (Other)

Outcomes

Primary Outcomes

Mean differences in joint range of motion expressed in degrees of movement (hip, knee, ankle) measured by sensors (Inertial Measurement Units) between patients and healthy volunteers

Time Frame: Baseline (single time point)

Joint range of motion of the hip, knee, and ankle measured using inertial measurement units (IMUs) and expressed in degrees (°). The outcome represents the mean difference in joint range of motion between patients and healthy volunteers; higher values indicate greater angular excursion of the joint.

Secondary Outcomes

  • Average of the normalized enveloped of surface electromyography signals(Baseline (single time point))

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Sandro Iannaccone

Director of Department of Rehabilitation and Functional Recovery

IRCCS San Raffaele

Study Sites (1)

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