Clinical Trial of Lupeol for Mild-moderate Acne
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Acne lesion counts as a measure of efficacy
研究概览
简要总结
For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over the age 15 who were clinically diagnosed with mild to moderate acne vulgaris
排除标准
- •; known pregnancy or lactation, any medical illness that might influence the results of the study, a previous history of oral acne medication or surgical procedures including laser treatment within 6 month and topical medication within 4 weeks of study enrollment.
研究组 & 干预措施
Lupeol
Patients are supposed to apply lupeol on one side of face two times per day for 8 weeks
干预措施: Lupeol (Drug)
Control vehicle
Patients are supposed to apply vehicle control to another side of face two times per day for 8 weeks
干预措施: Control vehicle (Drug)
结局指标
主要结局
Acne lesion counts as a measure of efficacy
时间窗: 8 weeks after beginning of applications
Both inflammatory \& non-inflammatory acne lesions of both of their facial sides
次要结局
- Number of Participants with Adverse Events as a Measure of Safety and Tolerability(8 weeks after beggning of applications)
研究者
Dae Hun Suh
Professor
Seoul National University Hospital