Clinical Trial of Lupeol for Mild-moderate Acne

Not Applicable

Completed

Brief Summary: For the chemical lupeol isolated from eggplant, we applied it to one side of face, and applied vehicle control to another side for 8 -weeks. The study was performed in a 8-week, randomized controlled, split face fashion. Investigators evaluated safety and efficacy during baseline, 2 weeks, 4weeks, and 8 weeks after beginning of study.

Recruitment & Eligibility

Inclusion Criteria

Patients over the age 15 who were clinically diagnosed with mild to moderate acne vulgaris

Exclusion Criteria

; known pregnancy or lactation, any medical illness that might influence the results of the study, a previous history of oral acne medication or surgical procedures including laser treatment within 6 month and topical medication within 4 weeks of study enrollment.

Arm && Interventions

Group	Intervention	Description
Lupeol	Lupeol	Patients are supposed to apply lupeol on one side of face two times per day for 8 weeks
Control vehicle	Control vehicle	Patients are supposed to apply vehicle control to another side of face two times per day for 8 weeks

Primary Outcome Measures

Name	Time	Method
Acne lesion counts as a measure of efficacy	8 weeks after beginning of applications	Both inflammatory \& non-inflammatory acne lesions of both of their facial sides

Secondary Outcome Measures

Name	Time	Method
Number of Participants with Adverse Events as a Measure of Safety and Tolerability	8 weeks after beggning of applications	Among total patients enrolled in this study, number of patients either experiencing objective adverse events or subjective uncomfortableness were counted

Locations (1): Seoul National University Hospital
🇰🇷
Seoul, Korea, Republic of

Receive instant email notifications about changes in this clinical trial

Receive instant email notifications about changes in this clinical trial