A COMPARISON OF EFFICACY AND SAFETY OF KAYA KALPA VATI AND SEABUCK THORN OIL WITH ORAL METHOTREXATE AND TOPICAL STEROID IN CHRONIC PLAQUE PSORIASIS

Phase 4

Not yet recruiting

• Conditions: Psoriasis vulgaris,

• Registration Number: CTRI/2020/06/025658
• Lead Sponsor: National Institute of Medical Sciences and Research Centre

Brief Summary

This study is a randomised interventional trial to compare the safety and efficacy of kaya kalpa Vati 2 tab thrice daily and sea buck thorn oil twice application with oral methotrexate 15mg once weekly and topical mometasone cream twice application for 16 weeks in 122 patients with chronic plaque psoriasis that will be conducted in NIMS Jaipur in India. The primary outcome measures will be reduction in PASI and improvement in DLQI at 8 weeks. The secondary outcome will be reduction in PASI score and improvement in DLQI at 16 weeks.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-01-06
• Study Start: 2020-10-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

• 1.Patient with chronic plaque psoriasis.
• 2.Psoriasis of both sex and age group more than 18 years.
• 3.All newly diagnosed and old cases of psoriasis.
• 4.Patients with PASI(psoriasis area severity index) score above10-12.
• 5.Patients with involvement of >10% body surface area.

Exclusion Criteria

• Patient who do not give consent for the study.
• Patient on any therapy of psoriasis for past 3 months.
• 3.Patient having any other chronic debilitating diseases or other chronic skin disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in PASI score	8weeks
Improvement in DLQI	8weeks

Secondary Outcome Measures

Name	Time	Method
Reduction in PASI score	Improvement in DLQI

Trial Locations

Locations (1)

National Institute of Medical Science and Research; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of Medical Science and Research

🇮🇳Jaipur, RAJASTHAN, India

dr Savita Agrawal

Principal investigator

9509097801

drshilpysavi@yahoo.com