Cross-cultural Validation of the German Version of the Amsterdam Instrumental Activities of Daily Living Questionnaire® in Elderly People With and Without Mild Neurocognitive Disorder
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 96
- Locations
- 1
- Primary Endpoint
- Change from baseline on the Amsterdam IADL Questionnaire short German version at two to four weeks
Study Overview
Brief Summary
Pretest and validation of the German version of the Amsterdam instrumental activities of daily living questionaire short in elderly people with normal cognition, mild cognitive impairment (MCI) or mild dementia in the German speaking part of Switzerland.
The aim is to investigate the psychometric properties of the final Amsterdam instrumental activities of daily living questionaire short (A-IADL-Q-SV) German.
Participants with normal cognition will be recruited in the community and participants with MCI and mild dementia in three memory clinic settings.
Detailed Description
Pretest:
Initially, five clinicians in the field will be asked to give feedback on the A-IADL-Q-SV German. Issues that need to be discussed include clarity of 1) answer options 2) the gradient of difficulty 3) activities or sentences. Adjustments will be made if necessary and documented.
At least five knowledgeable informants will then complete the A-IADL-Q-SV while thinking out loud and are asked to write down comments and issues on 1) the relevance of all items, 2) the applicability / meaning of the activities in Switzerland and 3) the understandability of the questions. The results will be reviewed in order to identify whether translation modifications will be necessary (e.g. rewording of items/response options). Additionally, the completed questionnaires will be explored to detect high proportions of missing items or single responses. If adjustments will be made, they will be discussed with the developer to finalize the translated German version.
Validation:
The A-IADL-Q-SV German will be tested in the community (people with normal cognition)and three memory clinic settings (people with MCI, mild dementia) including a total of 100 informants from people with normal cognition, MCI and mild dementia.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 60 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Living in the community
- •Ability to understand the purpose of the study and to consent
- •Knowledgeable informant available
- •Signed informed consent to participate in the study
Exclusion Criteria
- •Moderate and severe cognitive decline (MMSE < 20) (people with MCI, mild dementia)
- •Cognitive decline suspect based on telephone screening (people with normal cognition)
- •Cognitive decline due to other causes than Alzheimer's disease, vascular dementia (e.g. neurological diseases, trauma, delirium)
- •Diagnosed Depression
- •Diagnosed Alcohol or Drug Misuse
Outcomes
Primary Outcomes
Change from baseline on the Amsterdam IADL Questionnaire short German version at two to four weeks
Time Frame: Follow-up after two to four weeks
Impairment in instrumental activities of daily living. Based on item response theory (IRT) the latent trait score is calculated with a mean of zero and standard deviation of one. The resulting score ranges from 20 to 80 with lower scores indicating poorer performance.
Amsterdam IADL Questionnaire short German version
Time Frame: Baseline
Impairment in instrumental activities of daily living. Based on item response theory (IRT) the latent trait score is calculated with a mean of zero and standard deviation of one. The resulting score ranges from 20 to 80 with lower scores indicating poorer performance.
Secondary Outcomes
- Mini Mental State Examination(Baseline)
- Cumulative Dementia Rating(Baseline)
- Depression im Alter Scale (DIA-S)(Baseline)
- Lawton Brody Instrumental Activities of Daily Living Scale(Baseline)
- Informant Questionnaire for Cognitive Decline in the Elderly (IQCODE) short(Baseline)
Investigators
Marina Bruderer
Principal Investigator
Zurich University of Applied Sciences