Investigating the effects of nimodipine on spinal reflex measures in humans
Not Applicable
- Conditions
- Healthy individuals and individuals with spasticitySigns and Symptoms
- Registration Number
- ISRCTN63413322
- Lead Sponsor
- niversity of Copenhagen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
1. Age 18 years old and over
2. Adults capable of providing informed consent for participation
3. Healthy volunteers will be recruited in the first part of the project
4. In the second part of the project, individuals with symptoms of muscle overactivity (spasticity/spasms/cramps/dystonia) due to CNS damage are recruited
Exclusion Criteria
1. Hypotension (systolic blood pressure <100mmHg)
2. Known impaired liver function, cerebral edema, or significantly increased intracranial pressure
3. Antispastic medication that cannot be paused, or recent botox injections
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method