Metabolic Equivalent of Task (MET) in the Preoperative Assessment in Aortic Surgery

Completed

• Conditions: Aortic Diseases
• Interventions: Diagnostic Test: MET

• Registration Number: NCT03617601
• Lead Sponsor: Triemli Hospital

Brief Summary

Reliable prediction of the preoperative risk is of crucial importance for patients undergoing vascular operations. The assessment of the metabolic equivalent of task (MET) is an easy clinical evaluation of the functional capacity of an individual. A MET is defined as the resting metabolic rate, that is the amount of the consumed oxygen at rest. According to the MET concept a patient would be considered as "fit for surgery" when the stairs of two flights can be climbed and the housework can be fully managed by oneself.

Hypothesis: Patients with a functional capacity over 4 MET (fit for surgery) have less perioperative complications with the focus on cardiac pathology than patients with less than 4 MET during aortic operations.

Patients and Method: Retrospective analysis of a single center unit of 296 patients undergoing open or endovascular aortic repair.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05
• Primary Completion: 2016-08
• Study Completion: 2018-01
• Status Verified: 2018-07
• Study First Submitted: 2018-07-06
• Study First Submitted QC: 2018-08-03
• Last Update Submitted: 2018-08-03
• Study First Posted: 2018-08-06
• Last Update Posted: 2018-08-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 296

Inclusion Criteria

• Data of all patients after open and endovascular aortic repair of the descending aorta from May 2009 till March 2016

Exclusion Criteria

• Data of all patients with isolated operations on the ascending aorta or aortic arch

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
> 4 MET	MET	Patients with functional capacity over 4 MET
< 4 MET	MET	Patients with functional capacity under 4 MET

Primary Outcome Measures

Name	Time	Method
Survival	up to ten years	Mean survival during the whole follow up period of both groups, patients with less and more than 4 MET

Secondary Outcome Measures

Name	Time	Method
Perioperative complications	up to 30 days postoperatively	Complications include perioperative myocardial infarction and stroke, re-operation during first admission (divided in greater and smaller re-operations)
Coronary artery bypass grafting, percutaneous coronary intervention/Stenting	up to ten years	Interventions including revascularisation or other kind of heart surgery or treatment because of cardiac pathology