A randomized controlled clinical trial for Qing-Gan Huo-Xue decoction in the treatment of alcoholic liver disease

Not Applicable

Completed

• Conditions: Alcoholic Liver Disease

• Registration Number: ITMCTR2000003519
• Lead Sponsor: onghua Hospital affiliated to Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged 18-70 years old;
2. The alt, AST or ? - GT were 1.5 times higher than the normal value;
3. Those who did not take relevant drugs within one week
4. Those who deny that hypertension, diabetes, cardiovascular and cerebrovascular diseases need to take all kinds of Western medicine for a long time;
5. During the study period, there was no pregnancy plan or postpartum non lactation period;
6. Normal mental and intelligence can cooperate with the researcher;
7. Informed consent and willing to accept the treatment plan.

Exclusion Criteria

1. Other liver diseases such as hepatitis B and C were found;
2. Those who relapsed drinking during the treatment;
3. Those who participated in other clinical studies or used other treatment schemes during the observation period;
4. Use other drugs by oneself during case observation;
5. Failure to complete follow-up or withdrawal from treatment due to other reasons;
6. During the study period, patients with severe cerebrovascular disease, hematopoietic system and mental diseases;
7. Pregnant women during observation;
8. Autoimmune liver disease, diabetic endocrine fatty liver disease, drug-induced liver disease, toxic hepatitis, liver cancer, nonalcoholic fatty liver disease, hepatorenal failure, occult hepatitis, liver disease with unknown causes;
9. Allergic to polyene phosphatidylcholine and / or traditional Chinese medicine;
10. Those who can't insist on completing the treatment or main observation indexes.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Procollagen III;Hyaluronic Acid;Laminin;?-glutamyl transpeptidase;Collagen IV;tumor necrosis factor alpha;alpha smooth muscle actin;Alkaline phosphatase;TCM syndrome efficacy;APRI Score;Total bilirubin;Fibrosis 4 Score;Direct bilirubin;Alanine aminotransferase;liver stiffness measurement;Aspartate aminotransferase;Albumin;Mean Corpuscular Volume;

Secondary Outcome Measures

Name	Time	Method
Total Cholestero;Triglycerides;