Comparison of honey and chlorhexidine mouthwashes on the Patients' oral care in IC
- Conditions
- Condition 1: oropharyngeal colonization. Condition 2: oropharyngeal colonization. Condition 3: oropharyngeal colonization. Condition 4: oropharyngeal colonization.Bacterial pneumonia, not elsewhere classifiedPneumonia due to Klebsiella pneumoniaePneumonia due to PseudomonasPneumonia due to staphylococcus
- Registration Number
- IRCT2016012412257N4
- Lead Sponsor
- Vice- chancellery for Research, Zanjan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Age between 18-65 years, New patients will admit to the ICU with an endotracheal tube intubation and mechanical ventilation undergo less than 12 hours previously, and have at least 4 days of mechanical ventilation.
Exclusion criteria:
Re-intubation and Re-admission to the ICU; transfer from another ICU; patients with pneumonitis and other systemic infections; a confirmed diagnosis of lung cancer; a evident signs of airway aspiration; a diagnosed thrombocytopenia (platelet count less than 40 and/or a INR>2 or other coagulopathy); anticoagulant therapy;a confirmed diagnosis of immunosuppression; high FBS, a known hypersensitivity to CHX and honey and other complication related to mouthwash solution used to in this study; leukopenia, HIV; pregnant women; organ transplant patients; oral mucositis; advanced periodontal disease; long term steroid therapy; Oral and maxillofacial surgery; extensive burns; contraindication for semi fowlers' position; absence of inform consent.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oropharyngeal colonization. Timepoint: befor intervention, 48 and 96 hours after intervention. Method of measurement: blood agar and EMB medium.
- Secondary Outcome Measures
Name Time Method