IRCT2016012412257N4CompletedPhase 3
A Comparative effectiveness of honey 12.5% and chlorhexidine 0.2% mouthwash on the oropharyngeal bacterial colonization in mechanically ventilated Patients in ICU: A randomized control trial
Vice- chancellery for Research, Zanjan University of Medical Sciences0 sites60 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Enrollment
- 60
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 65 years (—)
- Sex
- All
Inclusion Criteria
- •Age between 18-65 years, New patients will admit to the ICU with an endotracheal tube intubation and mechanical ventilation undergo less than 12 hours previously, and have at least 4 days of mechanical ventilation.
- •Exclusion criteria:
- •Re-intubation and Re-admission to the ICU; transfer from another ICU; patients with pneumonitis and other systemic infections; a confirmed diagnosis of lung cancer; a evident signs of airway aspiration; a diagnosed thrombocytopenia (platelet count less than 40 and/or a INR>2 or other coagulopathy); anticoagulant therapy;a confirmed diagnosis of immunosuppression; high FBS, a known hypersensitivity to CHX and honey and other complication related to mouthwash solution used to in this study; leukopenia, HIV; pregnant women; organ transplant patients; oral mucositis; advanced periodontal disease; long term steroid therapy; Oral and maxillofacial surgery; extensive burns; contraindication for semi fowlers' position; absence of inform consent.
Exclusion Criteria
- Not provided
Investigators
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