To study the effect of drugs given directly into the arteries feeding the liver cancer along with heat induced changes on liver cancer outcome as assessed by Computed tomography.
Phase 4
- Conditions
- Health Condition 1: K768- Other specified diseases of liver
- Registration Number
- CTRI/2022/10/046766
- Lead Sponsor
- Indian Council Of Medical Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. BCLC stage B with Child Pugh A or B
2. Main portal vein patent
3. No extrahepatic spread
4. No previous treatment for Hepatocellular Carcinoma
5. Coagulation parameters suitable for TACE.
Exclusion Criteria
1. Uncorrectable Coagulopathy
2. Refractory Ascites
3. Hepatic Encephalopathy
4. Esophageal/ Variceal bleeding
5. Allergic to contrast
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1] modified Response Evaluation Criteria in Solid Tumors (mRECIST) used for response evalution <br/ ><br>2]at 1,3,6,12 months after intervention by Triple phase CT /MRI scan.Timepoint: 12 months.
- Secondary Outcome Measures
Name Time Method liver function tests <br/ ><br> <br/ ><br>Timepoint: 1,3,6,12 months after intervention