A phase I study of pemetrexed and gefitinib in chemotherapy naive elderly patients with non- small cell lung cancer harboring EGFR mutatio
Phase 1
- Conditions
- on-Small Cell Lung Cancer
- Registration Number
- JPRN-UMIN000006273
- Lead Sponsor
- ational Hospital Organization Kyushu Medical Center Department of Respiratory Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 11
Inclusion Criteria
Not provided
Exclusion Criteria
1)Serious infections 2)Serious clinical problems 3)Interstitial pneumonia/lung fibrosis on chest CT 4)Active concomitant malignancy 5)Symptomatic brain metastasis 6)Massive pericardial, pleural effusion, ascites 7)Previous drug allergy 8)Those judged to be not suitable by the attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maximum tolerated dose (MTD) of pemetrexed and gefitinib
- Secondary Outcome Measures
Name Time Method Anti tumor efficacy