Cognitive-behavioural therapy for treatment-resistant depression: early intervention study

Not Applicable

Completed

• Conditions: Depression; Mental and Behavioural Disorders; Depressive episode

• Registration Number: ISRCTN53305823
• Lead Sponsor: Record Provided by the NHSTCT Register - 2007 Update - Department of Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09-28
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

24 depressed NHS patients, aged 18 - 65 years, will be recruited from routine referrals to the Newcastle CBT Centre (NCBTC) and secondary care mental health services within the 3Ns Trust.
1. Adults aged 18 - 65 years
2. Major depressive episode as the primary diagnosis, first or second major episode, lasting at least 12 months duration
3. Moderate or severe depression symptoms
4. Treatment-resistance to at least one course of anti-depressant previously administered at an adequate dose for adequate period, treatment resistance to other primary care interventions

Exclusion Criteria

1. Previous individual or group CBT following a recognised protocol within secondary care services
2. Three or more major episodes of depression
3. People with bi-polar disorder, psychosis, learning disability, borderline personality disorder, alcohol or addiction problems

Study & Design

• Study Type: Interventional
• Study Design: Not specified