Study of Risk Factors for Developing Inhalation Pneumonia After Inhalation

• Conditions: Risk Factor; Inhalation Pneumonia

• Registration Number: NCT03108430
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Inhalation pneumonia (PI) is common in clinical practice but is rarely studied. For example, there are no data on the incidence of pneumonia after inhalation and risk factors or protective factors to develop one since it is known that anyone who inhaled does not necessarily develop an IP. There is no data on the benefit of treating inhalation by antibiotic therapy pre-emptively although this practice is common. In this context, this observational study wishes to take stock of the situation on the subject in order to determine what actions to implement to prevent IP.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-22
• Study First Submitted: 2017-03-31
• Status Verified: 2017-04
• Study First Submitted QC: 2017-04-05
• Last Update Submitted: 2017-04-05
• Study First Posted: 2017-04-11
• Last Update Posted: 2017-04-11
• Primary Completion: 2017-08-21
• Study Completion: 2017-08-21

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• In intensive care: Any intubated patient who presented:
• It is a coma with GCS ≤ 12 without VAS protection, whatever the duration
• Either a proven inhalation, defined by the presence in the VAS of gastric fluid or food
• Either a suspected inhalation, defined by the extrahospital anamnesis
• In medicine :
• Any wrong way (defined by a reflex cough when taking food)
• Coma without intubation, regardless of duration or depth

Exclusion Criteria

• Patients with VAP

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Calculate the annual incidence of PI, the incidence of PI in inhaled patients (in each subgroup), and analyze the risk factors by logistic regression, based on the number of patients hospitalized during the study period.	1 day

Trial Locations

Locations (1)

CHU Amiens Picardie; 🇫🇷 Amiens, Picardie, France