Hematological Indices in Pre-eclampsia

Not Applicable

• Conditions: Health Condition 1: O140- Mild to moderate pre-eclampsia

• Registration Number: CTRI/2020/07/026623
• Lead Sponsor: All India Institute Of Medical Sciences Raipur

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Pregnant women of age 18-40years, with singleton pregnancy and 13-20 weeks gestational age, attending antenatal care: Outpatient department (OPD) and/or Inpatient department (IPD) in department of Obstetrics and Gynecology at All India Institute of Medical Sciences, Raipur and giving fully valid consent to participate in the study.

Exclusion Criteria

â??Age < 18 years and > 40 years

â??Multi fetal pregnancy

â??Women who have co existing medical illness

oChronic Hypertension

oDiabetes mellitus

oChronic liver disease

oChronic Kidney disease

oEstablished Cardiovascular disease

oCollagen vascular disease

oHematological disease

oOngoing infection or systemic inflammatory conditions

oAutoimmune disease

â??History of Smoking, alcoholism and drug abuse

â??Pregnancy complications like membrane rupture or intrauterine fetal death

â??History of fever, HELLP.

â??Patient refusal to participate in study

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study the role of the Hematological indices such as Neutrophil to Lymphocyte ratio, Platelet to lymphocyte ratio, Mean Platelet Volume, Platelet distribution width, Red cell Distribution Width and Delta Neutrophil Index as predictors of pre-eclampsia.Timepoint: from the time of recruitment till 6 weeks postpartum

Secondary Outcome Measures

Name	Time	Method
a) To study the role of Hematological indices such as Neutrophil to Lymphocyte ratio, Platelet to lymphocyte ratio, Mean Platelet Volume, Platelet distribution width, Red cell Distribution Width and Delta Neutrophil Index as markers of severity in women with pre-eclampsia. <br/ ><br>b) To determine the diagnostic accuracy of Neutrophil to Lymphocyte ratio, Platelet to lymphocyte ratio for the diagnosis of severe and non-severe pre-eclampsia. <br/ ><br>Timepoint: from the time of recruitment till 6 weeks postpartum