Comparing the analgesic efficiency among paracetamol, ibuprofen and paracetamol-ibuprofen given preoperatively by monitoring vitals intraoperatively and VAS score postoperatively in orthopedic surgeries.
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/06/069194
- Lead Sponsor
- Government Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion criteria
1 ASA class I or II
2 Age from 18 to 70 years either sex
3 Measuring 150 to 180 cm height, with body mass index BMI of 18 to 35 kg per m2
4 Patients undergoing elective and emergency orthopaedic surgeries requiring spinal anaesthesia
1 All contraindications to spinal analgesia including bleeding diathesis, infection at the puncture site, spinal deformity, patient on anticoagulants, pre existing neurological deficits in lower extremities, unwillingness to give consent.
2 Surgical duration more than 2 hours
3 Sensory blockade inadequate for surgery.
4 Patients having cardiac rhythm abnormalities.
5 History of alcoholism, drug abuse, and psychiatric disorders.
6 History of allergy to any of the study drugs.
7 Hepatic disease, renal disease, cardiopulmonary disease, hypertension, diabetes, central or peripheral nervous system disorders.
8 Chronic pain patients undergoing treatment with opioid analgesic.
9 Pregnant patients.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method