The effect of sodium chloride intake on blood pressure response to coffee
Completed
- Conditions
- Hypertension10057166
- Registration Number
- NL-OMON37848
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
Signed informed consent.
At least 18 years of age.
Exclusion Criteria
Use of any medication or recreational drugs (exept oral anticonception in female participants)
Hypertension (defined as SBP > 140 mmHg and/or DBP > 90 mmHg as measured after at least 5 minutes in supine position by standard auscultatory measurements)
Difference in blood pressure between the two arms of 10 mmHg or more (systolic)
Alcohol consumption > 2 units/day
Any cardiovascular abnormality as detected during routine history and physical examination.
BMI > 25
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>response to coffee intake of blood pressure Dinamap and Nexfin) and cardiac<br /><br>output (Pulse contour method applied to continuous blood pressure signal that<br /><br>is measured at the finger using Nexfin)</p><br>
- Secondary Outcome Measures
Name Time Method <p>sodium and creatinine excretion in urine; plasma caffeine concentration before<br /><br>and 2 hours after intake of 2 cups of coffee</p><br>