Diabetes Bootcamp; Sport intervention in patients with diabetes type 2 and the association with the gut microbiota. - Diabetes Bootcamp

Vrije Universiteit Medisch Centrum0 个研究点目标入组 15 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•1. Patients with type 2 diabetes
•2. Male or female (post-menopausal)
•3. Age above 45 years and below 70 years
•4. BMI >30 kg/m2
•5. Metformine monotherapie (no insulin or other glucose lowering medication)
•6. Stable medication use
•7. Stable tension regulation (with or without medication)
•8. Stable body weight during 6 months before enrolment in the study (<2 kg shifts)
•9. Subjects should be able to give informed consent
•10. HbA1c < 80 mmol/mol or < 8,6%

•1. A history of cardiovascular event (Cerebrovascular event, myocardial infarction or pacemaker implantation)
•2. Severe-very severe lung emphysema (GOLD stage III-IV)
•3. Use of any antibiotics or proton pump inhibitor (PPI) in the past three months
•4. Use of any other antidiabetic medication besides metformin (e.g. SU-derivates, insulin)
•5. Use of a platelet inhibitor or cumarin derivate during
•6. Subjects participated in a lifestyle programme in the past 6 months (diet or exercise)
•7. Contraindications of iloprost (ilomedine®): increased risk of bleeding; severe coronary artery disease or instable AP; heart failure (NYHA class II-IV); severe arrhythmias; suspected left decompensation; hypersensitivity to the active substance or to any of the excipients
•8. Contraindications of insulin(NovoRapid®): hypersensitivity to the active substance or to any of the excipients

发起方