NCT00469690已完成4 期
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract Patients: Trough Drug Effects
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Aqueous concentrations
研究概览
简要总结
The purpose of this study is to compare the ability of two different topical NSAIDs (non-steroidal anti-inflammatory medications used for pain relief) to reach the back of the eye and to stop inflammation. The study will conclude on the day of your cataract surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy Male/Female 21 years of age of older.
- •Patient understands and is willing to sign the written informed consent form
- •Likely to complete the entire course of the study.
- •Patient is scheduled to undergo cataract surgery
- •Female patients of childbearing potential must have had a regular menstrual cycle prior to study entry (a female is considered of childbearing potential unless she is postmenopausal, without a uterus and/or both ovaries, or has had a bilateral tubal ligation).
- •Patient is willing and able to administer eye drops and record the times the drops were instilled
排除标准
- •Patient has been using a topical NSAID within 1 week of study entry
- •Patient has a known sensitivity to any of the ingredients in the study medications
- •Patient has sight in only one eye
- •Patient has a history of previous intraocular surgery
- •Patient's doctor has determined they have a condition (i.e., UNCONTROLLED systemic disease) or are in a situation that may put them at significant risk, confound the study results or may interfere significantly with their participation in the study
- •Female patients who are pregnant, nursing an infant or planning a pregnancy
- •Patients who are currently involved in another investigational study or have participated in one within the 30 days prior to entering this study
研究组 & 干预措施
1
Other
干预措施: Acular, Xibrom (Drug)
2
Other
干预措施: Acular, Xibrom (Drug)
结局指标
主要结局
Aqueous concentrations
时间窗: 8 months
次要结局
- PGE2 Inhibition(8 months)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
4 期
Aqueous Concentrations and PGE2 Inhibition of Ketorolac 0.4% vs. Bromfenac 0.09% in Cataract PatientsCataractNCT00347503Innovative Medical
已完成
不适用
on-steroidal anti-inflammatory drugs vs Steroids in the post operative management of inflammation following uncomplicated cataract surgeryEye DiseasesSurgerycataractPACTR201701001971511Dr Egagifo Ochuko100
尚未招募
3 期
To compare which drug works better in treatment of plaque psoriasis between 2 percent crisaborole cream vs 0.1 percent betamethasone valereate ointment.CTRI/2024/08/072562GURUPRAKASH A V
招募中
3 期
Topical nonsteroidal anti-inflammatory drug effect on patients with pseudoexfoliation syndrome during cataract surgeryAge-related cataractAnterior segment inflammation and complications after cataract surgery in patients with pseudoexfoliation syndrome.IRCT20160919029871N3Guilan University of Medical Sciences96
已完成
3 期
Topical N-Acetylcysteine and Zinc Oxide in the Treatment of Diaper DermatitisDiaper dermatitisIRCT20181208041882N6Yazd University of Medical Sciences44