Clarification effect of l-menthol sprayed onto the early gastric cancer during laser endoscopy

Not Applicable

• Conditions: early gastric cancer

• Registration Number: JPRN-jRCTs021200027
• Lead Sponsor: Hikichi Takuto

Brief Summary

In laser endoscopic observation, the color difference between EGC and the surrounding mucosa was 5 or more in 100% of cases both before and after l-menthol application, showing no difference between the cases before and after the application. However, the color difference was significantly increased by l-menthol spraying, indicating that l-menthol was effective in clarifying early gastric cancer in the subjective evaluation by the physician.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-11-12
• Study Completion: 2022-03-02
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

1) Patients who provide written informed consent to participate in the research.
2) Men and women who are 20 years of age or older when consent is obtained.
3) Patients are histologically diagnosed as a gastric cancer.
4) EGC lesion has any of the following.
(1) Macroscopic intramucosal cancer (cTIa) of 3 cm or less, differentiated cancer without ulceration (UL0)
(2) Macroscopic intramucosal cancer (cTIa) of 3 cm or less, differentiated cancer, with ulceration (UL1)
(3) Macroscopic intramucosal cancer (cTIa) of 2 cm or less, undifferentiated cancer without ulceration (UL0).

Exclusion Criteria

1) A lesion that does not fit in one visual field of an endoscopic image.
2) Lesions on the cardia or pylorus.
3) Easy bleeding lesion.
4) Patients with a history of hypersensitivity to l-menthol.
5) Patients who have been judged by the main reseacher to be inappropriate for inclusion in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified