ACTRN12610000917033已完成不适用
To compare the effects of ritonavir-boosted atazanavir (AZV 300mg / RTV 100mg once daily) to ritonavir-boosted darunavir (DRV 800mg / RTV 100mg once daily) over 4 weeks on postprandial lipids in healthy volunteers.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1.Provision of signed, informed consent
- •2.Adults taking their normal diet” (stable intake for each participant) with a stable weight and no desire to lose or gain weight
- •3.Body mass index between 20 and 30 kg/m2
- •4.Fasting triglycerides < 2.0 mmol/l
- •5.Fasting total cholesterol < 6.0 mmol/l
排除标准
- •6.HIV infection (antibody, western blot, proviral DNA)
- •7.Use of any medication contra-indicated with RTV, AZV or DRV
- •8.Use of lipid-lowering therapy
- •9.Use of anti-hypertensive therapy
- •10.Diabetes mellitus (fasting glucose > 7.0 mmol/l or a prior diagnosis of diabetes)
- •11.Serum hepatic transaminases (ALT / AST) greater than 3 times the upper limit of normal
- •12.Pregnancy or breast feeding
研究者
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