VolumE maNagement Under body composition monitoring in critically ill patientS on CRRT:Randomized-controlled trial (VENUS trial)

Not Applicable

Completed

• Conditions: Symptoms, signs and abnormal clinical and laboratory findings, NEC

• Registration Number: KCT0002534
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2020-10-01
• Last Update Posted: 4 April 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 208

Inclusion Criteria

1) Patient Inclusion Criteria;
Patients will be eligible for INCLUSION in the study if ALL the following criteria are met;
? The treating clinician believes that the patient requires CRRT for acute renal failure.
? The treating clinicians anticipate treating the patient with CRRT for at least 72 hours.
? Informed consent has been obtained.
? The patient fulfils ONE of the following clinical criteria for initiating CRRT:
Oliguria (urine output < 100ml/6hr) that has been unresponsive to fluid resuscitation measures
- Hyperkalemia ([K+]>6.5mmol/L)
- Severe academia (pH < 7.2)
- Urea > 25mmol/L
- Creatinine > 300umol/L
- Clinically significant organ edema in the setting of ARF (eg: lung)

Exclusion Criteria

1) Patient Exclusion Criteria
Patients will be EXCLUDED from the study if, in the opinion or knowledge of the responsible clinician ANY of the following criteria are present:
? Patient age is < 18years
? Death is imminent (<24 hours)
? There is a strong likelihood that the study treatment will not be continued in accordance with the study protocol.
? The patient has been treated with CRRT or other dialysis previously during the same hospital admission.
? The patient has been on maintenance dialysis prior to the current hospitalization.
? Any other major illness that, in the investigator’s judgement, will substantially increase the risk associated with the subject’s participation in this study.

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To investigate the mortality rate between Inbody S10 and Control groups;To investigate the reaching rate to euvolemia after 1 week from CRRT initiation

Secondary Outcome Measures

Name	Time	Method
To investigate the safety for Inbody S10