Efficacy of flexible Progestin primed ovarian stimulatio

Not Applicable

Completed

• Conditions: Health Condition 1: O090- Supervision of pregnancy with history of infertility

• Registration Number: CTRI/2022/09/045274
• Lead Sponsor: Indira IVF Hospital Pvt Ltd

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-08-14
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 91

Inclusion Criteria

1)All voluntary egg donors giving consent to participate in the study.

2) Age 21 to 35 yrs.

3) Having at least one healthy living child.

4) AFC 10 to 25

Exclusion Criteria

1)Poor ovarian reserve defined as antral follicle count (AFC) < 5

2) BMI >30 kg/m2

3) Having following gynaecological conditions like ovarian endometriosis, Oestrogen dependent tumour like endometrial or breast carcinoma.

4) Received luteal phase GnRH agonist use for suppression

5) Uncontrolled diabetes, hypertension or thyroid disorder

6) Diagnosed to be sero-positive for HIV, HBSAg, or HCV

7) Active infection of Covid 19 by RT-PCR

8) Known genetic or hereditary disease in herself or her child

9) Diagnosed haemoglobinopathy like Thalassemia or Sickle cell disease.

10) Any follicle measuring =9 mm on D2/ D3 scan.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The total proportion of cases having premature LH surge <br/ ><br>Timepoint: before ovulation trigger

Secondary Outcome Measures

Name	Time	Method
Retrieval rateTimepoint: on day of pick up;average duration of stimulationTimepoint: day of trigger injection;Comparison of total gonadotrophin dose requirementTimepoint: at time of trigger;Cost-effectivenessTimepoint: on day of ovum pick up;M2 rateTimepoint: on day of pick up;total cost of stimulationTimepoint: on day of ovum pick up