Comparing Visual Outcomes for cylindrical power correction using 2 advanced techniques for laser vision correction : LASIK & SMILE

Phase 4

Conditions: Health Condition 1: null- Patients with compound myopic astigmatism wanting to undergo refractive surgery

Registration Number: CTRI/2017/11/010607

Lead Sponsor: DrDRamamurthy

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1. Subjects 18 years of age or older.

2. Myopia requiring (a) refractive error correction of -0.5 to -8.0 manifest refraction sphere with (b) astigmatism correction of -1.0 D to -5.0Dmanifestrefraction cylinder

3. Intended treatment is targeted for emmetropia.

4. Pre-surgery BCVA of 0 logarithm of the minimum angle of resolution (logMAR) (20/20) or better.

5. Willing and able to complete all post-surgery visits.

Exclusion Criteria

1. Pregnancy or lactation, current or planned, during the course of the study.

2. Mixed astigmatism refractive error.

3. Degenerations of structure of the cornea including diagnosed keratoconus, formefrustekerataconus or pellucid marginal degeneration.

4. History or evidence of active or inactive corneal or other anterior segment disease (e.g, herpes simplex keratitis, recurrent erosionsyndrome).

5. Weakened immune system, including diagnosed collagen vascular, autoimmune or immunodeficiency disease.

6. Co existing Retinal or Optic nerve head co morbidities which could affect the final visual outcome.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective of the study is to evaluate percentage of eyes with manifest refraction cylinder â?¤ 0.5 D at 3 months using the two techniques.Timepoint: The primary objective of the study is to evaluate percentage of eyes with manifest refraction cylinder â?¤ 0.5 D at 3 months using the two techniques.

Secondary Outcome Measures

Name	Time	Method
1. Mean refractive cylinder at 3 months <br/ ><br>2. Percentage of eyes with atleast 1 line gain in BCVA at 3 months <br/ ><br>3. Percentage of eyes with UCVA of 20/20 or better at 3 months <br/ ><br> <br/ ><br>Timepoint: 3 months