The effect of platelet rich plasma and vitamin C on rotator cuff tears

Phase 2

Conditions: Partial thickness rotator cuff tear.
Rotator cuff tear or rupture, not specified as traumatic
M75.1

Registration Number: IRCT20230821059205N1

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 110

Inclusion Criteria

Men and women between 18 and 70 years old
Patients who had been diagnosed for 6 months
Patients with PTRCTs located in the supraspinatus tendon diagnosed via MRI.

Exclusion Criteria

Elderly patients over 70 years of age
Rotator cuff tears following fracture and trauma
History of revision arthroscopy or previous reconstructive surgery
History of PRP injection or other drug interventions, including intra-articular corticosteroid injection
Pregnant patients
History of mental disorders, cardio-cerebrovascular disease
Shoulder pain induced by non- rotator cuff tear
Patients treated with drugs that interfere with vitamin C
Presence of active infection
Hemoglobin <7.0 g?dl or platelets < 150,000?µ

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity score of patients on visual analog scale. Timepoint: At the beginning of the study, 1 month and 3 months after the intervention. Method of measurement: Visual analog scale.;American Shoulder and Elbow Surgeons (ASES) score. Timepoint: At the beginning of the study, 1 month and 3 months after the intervention. Method of measurement: American shoulder and elbow surgeons questionnaire,.;Constant Score. Timepoint: At the beginning of the study (before the start of the intervention), 1 month and 3 months after the intervention. Method of measurement: Constant Score.

Secondary Outcome Measures

Name	Time	Method
Visual analog scale. Timepoint: At the beginning of the study , 1 month and 3 months after the intervention. Method of measurement: Visual analog scale.;American Shoulder and Elbow Surgeons (ASES) score. Timepoint: At the beginning of the study, 1 month and 3 months after the intervention. Method of measurement: American shoulder and elbow surgeons questionnaire,.;Constant Score. Timepoint: At the beginning of the study , 1 month and 3 months after the intervention. Method of measurement: Constant Score.