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A Clinical Trial of KT07 Capsule in the U.S.A

Phase 2
Completed
Conditions
Influenza, Human
Interventions
Drug: KT07 Capsule
Other: Placebo
Registration Number
NCT02867358
Lead Sponsor
Yiling Pharmaceutical Inc.
Brief Summary

The purpose of this study is to investigate clinical efficacy of KT07 capsule in alleviation of fever and other symptoms including nasal congestion, sore throat, cough, aches and pains, fatigue, headache, chills or sweats in subjects with acute uncomplicated influenza.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
391
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
High dose of KT07 capsuleKT07 CapsuleIt will assess about 140 subjects with influenza at high dose KT07 (6 capsules each time, bid).
PlaceboPlaceboIt will assess 140 subjects with influenza using 6 capsules of placebo each time, bid as control.
Low dose of KT07 capsuleKT07 CapsuleIt will assess about 140 subjects with influenza at low dose KT07 (4 capsules of KT07 + 2 capsules of placebo each time, bid).
Low dose of KT07 capsulePlaceboIt will assess about 140 subjects with influenza at low dose KT07 (4 capsules of KT07 + 2 capsules of placebo each time, bid).
Primary Outcome Measures
NameTimeMethod
To investigate the improvement in reducing the duration of illness compared to placebo.Up to 19 days

Duration of illness is defined as: the length of time to alleviation of all symptoms.

The duration of alleviation is calculated from time 0 (first administration of study medication) to the time at which symptom is alleviated.

Secondary Outcome Measures
NameTimeMethod
The reduction in duration of alleviation of individual symptomUp to 19 days

From time zero to the time at which the symptom is less than or equal to mild and stable for at least 24 hours

Quality of life assessmentUp to 19 days

Based on the self-assessment questionnaire

Trial Locations

Locations (74)

Central Alabama Research

🇺🇸

Birmingham, Alabama, United States

Parkway Medical Center, LLC

🇺🇸

Birmingham, Alabama, United States

Cahaba Research, Inc.

🇺🇸

Birmingham, Alabama, United States

David Wever

🇺🇸

Pelham, Alabama, United States

Alliane Urgent Care

🇺🇸

Tolleson, Arizona, United States

Orange County Research Institute

🇺🇸

Anaheim, California, United States

Hope Clinical Research, Inc.

🇺🇸

Canoga Park, California, United States

Core Health Care Group

🇺🇸

Cerritos, California, United States

Aviva Research

🇺🇸

Escondido, California, United States

Lalla-Reddy Medical Corp.

🇺🇸

Fountain Valley, California, United States

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Central Alabama Research
🇺🇸Birmingham, Alabama, United States
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