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Clinical Trials/NCT04902924
NCT04902924CompletedNot Applicable

A Randomized Controlled Trial to Evaluate the Effectiveness of Repeated Cold- and Warm Water Immersion on Performance Recovery

University of Applied Sciences and Arts of Southern Switzerland2 sites in 1 country30 target enrollmentStarted: October 1, 2021Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
30
Locations
2
Primary Endpoint
Maximum Voluntary Isometric Contraction (N)

Study Overview

Brief Summary

The overall aim of this study is, to evaluate the effectiveness of repeated cold- and warm water immersion on performance recovery after muscle damage.

Detailed Description

Participants perform a muscle-damage protocol, which comprises 5x20 drop jumps. After the exercise protocol is finished, the participants will undergo one of three recovery interventions. Cold-water immersion, Warm-water immersion or the control-intervention. During the exercise protocol and the recovery intervention following parameters will be assessed: Blood oxygenation, Muscle oxygenation, heart-rate, skin temperature and core temperature.

Then, performance recovery will be assessed during the following 72 hrs (in a 24 hrs interval).

At each time-point, following measurements will be conducted: vertical-jump performance, maximum voluntary isometric contraction of the m.quadriceps femoris muscle, muscle swelling and delayed-onset of muscle soreness.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Basic Science
Masking
None

Eligibility Criteria

Ages
18 Years to 35 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Healthy participants
  • No surgeries
  • No previous injuries
  • Anticonceptiva allowed

Exclusion Criteria

  • Acute injuries or current pain situations
  • Cryophobia
  • Pregnancy
  • Raynaud syndrome
  • Medication intake

Outcomes

Primary Outcomes

Maximum Voluntary Isometric Contraction (N)

Time Frame: baseline to 72 hours

maximun voluntary isometric contraction of the knee extensor muscle will be assessed.

Delayed Onset of Muscle Soreness (DOMS)

Time Frame: baseline to 72 hours

delayed onset of muscle soreness will be measured using a 0-10 scale, where 0 indicated no soreness and 10 indicates maximum soreness of the knee extensor muscles

Muscle Swelling

Time Frame: baseline to 72 hours

swelling of the knee extensor muscle will be performed using a ultrasound device.

Creatine-kinase (U/l)

Time Frame: baseline to 72 hours

using a blood sample (6 ml), creatine-kinase will be assessed

Muscle Blood Oxygenation

Time Frame: through recovery intervention up to 30 minutes

Muscle oxygenation saturation (SmO2) of the knee extensor muscle will be measured using near-infrared spectroscopy device. Oxygenated haemoglobin (oxyHb), deoxygenated haemoglobin (deoxyHb) and total haemoglobin (TotHb) were assessed in arbitrary units and SmO2 was calculated as oxyHb/TotHb x 100 value (%)

Skin Temperature (°C)

Time Frame: through recovery intervention up to 30 minutes

Skin temperature will be measured using a near infrared thermography camera

Core Temperature (°C)

Time Frame: through recovery intervention up to 30 minutes

core temperature will be measured using temperature pill that will provide real time values from the gastrointestinal region

Maximum Voluntary Isometric Contraction (N)

Time Frame: baseline to 72 hours

maximun voluntary isometric contraction of the knee extensor muscle will be assessed.

Delayed Onset of Muscle Soreness (DOMS)

Time Frame: baseline to 72 hours

delayed onset of muscle soreness will be measured using a 0-10 scale, where 0 indicated no soreness and 10 indicates maximum soreness of the knee extensor muscles

Muscle Swelling

Time Frame: baseline to 72 hours

swelling of the knee extensor muscle will be performed using a ultrasound device.

Creatine-kinase (U/l)

Time Frame: baseline to 72 hours

using a blood sample (6 ml), creatine-kinase will be assessed

Muscle Blood Oxygenation

Time Frame: through recovery intervention up to 30 minutes

Muscle oxygenation saturation (SmO2) of the knee extensor muscle will be measured using near-infrared spectroscopy device. Oxygenated haemoglobin (oxyHb), deoxygenated haemoglobin (deoxyHb) and total haemoglobin (TotHb) were assessed in arbitrary units and SmO2 was calculated as oxyHb/TotHb x 100 value (%)

Skin Temperature (°C)

Time Frame: through recovery intervention up to 30 minutes

Skin temperature will be measured using a near infrared thermography camera

Core Temperature (°C)

Time Frame: through recovery intervention up to 30 minutes

core temperature will be measured using temperature pill that will provide real time values from the gastrointestinal region

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University of Applied Sciences and Arts of Southern Switzerland
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Ron Clijsen

Head of research

University of Applied Sciences and Arts of Southern Switzerland

Study Sites (2)

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