A study of ophthalmic artery flow dynamics across the clinical stages of primary open angle glaucoma
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 128
- 试验地点
- 1
- 主要终点
- Pusatility index, mean arterial peak velocity, resistivity index, mean flow velocity, diastolic flow velocity, ocular perfusion pressure
研究概览
简要总结
This study aims to detect glaucoma staging through ophthalmic artery flow examination. This could lead to a unique way of identifying the disease, leading to the modification in the existing screening cost (lowering) and chair time protocols. Research area targeting the circulatory aspects of optic disc and glaucoma can be further evolved, both at the functional and cellular level. Newer testing algorithms can be developed and experimented as next phase of research to long sustain
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects to be over 18 years of age Best corrected visual acuity 0.5 (6/19 Snellen fraction) or more in each eye No history of ocular trauma and/or surgery and/or inflammation within the last 6 months.
排除标准
- •o Ocular hypertension o Glaucoma other than POAG o Cataract o Diabetic retinopathy o Chronic retinal diseases o Any significant cardiac or pulmonary condition o Stenosis of the carotid arteries equal to and greater than 50%.
结局指标
主要结局
Pusatility index, mean arterial peak velocity, resistivity index, mean flow velocity, diastolic flow velocity, ocular perfusion pressure
时间窗: Pusatility index - baseline, mean arterial peak velocity - baseline, resistivity index - baseline, mean flow velocity - baseline, diastolic flow velocity - baseline, ocular perfusion pressure - baseline. All the data are collected simultaneously only once
次要结局
- Perimetry, Ocular Coherence Tomography, Intra-Ocular Pressure, Vision(Perimetry - baseline, Ocular Coherence Tomography - baseline, Intra-Ocular Pressure - baseline, Vision -baseline across the 4 groups. All the data are collected simultaneously, only once)
研究者
Avinash V Prabhu
MS Ramaiah University of Applied Sciences