Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.

Not Applicable

• Conditions: Eye Bruise; Hematoma; Surgical Wound; Surgery; Edema
• Interventions: Biological: Khat leaves

• Registration Number: NCT03917641
• Lead Sponsor: Sheba Medical Center

Brief Summary

The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery. Khat (Catha edulis) is a plant that is used mainly for chewing and has a known stimulating effect, some patients report major improvement after including these leaves in the compressions they use after surgery. Khat contains the chemical ingredients Cathine and Cathinone, which are amphetamine-like alkaloids and probably the main contributors for its active effects. Our main goal is to use compressions that include the Khat leaves and check their effect on reducing the edema and hematomas after oculoplastic surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-04
• Study First Submitted: 2019-04-01
• Study First Submitted QC: 2019-04-13
• Last Update Submitted: 2019-04-13
• Study First Posted: 2019-04-17
• Last Update Posted: 2019-04-17
• Study Start: 2019-07-01
• Primary Completion: 2020-07-01
• Study Completion: 2021-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Patients who underwent blepharoplasty and/or ptosis repair

Exclusion Criteria

• Patients who were operated on one eye only
• Patients who underwent a different surgery in each eye

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients after Oculoplastic surgery	Khat leaves	Each participant will use one compression with Khat leaves and another standard compression and will decide on which eye to use which compression. The compressions will be used for 10 minutes per every waking hour in the first 2 days post-op. The patient will take pictures of both his eyes in days 1,3 and 7 post operative days.

Primary Outcome Measures

Name	Time	Method
Edema	7 days post op	Improvement in edema in the Khat compression in comparison to standard compression by clinical evaluation.
Hematoma	7 days post op	Improvement in hematomas in the Khat compression in comparison to standard by compression by clinical evaluation.

Trial Locations

Locations (1)

Sheba_Medical_Center; 🇮🇱 Ramat Gan, Israel