To establish the effect of encapsulated nutrients on gut peptide secretion, glucose tolerance and appetite

Cambridge Institute for Medical Research (UK)0 个研究点目标入组 180 人开始时间: 2012年10月18日最近更新: 2017年9月4日

适应症

试验速览

暂无简介。

•1. Healthy male or female subjects, aged 18 to 65 years.
•2. BMI 18 to 45 kg/m2.
•3. Willingness to attend the CRF on 4-5 occasions at approximately 12 week intervals for administration of capsules.
•1. Male or female subjects, aged 18 to 65 years with T2DM or glucose intolerance as diagnosed by a previous OGTT and /or fasting glucose level and HbA1c level.
•2. BMI 18 to 45 kg/m2.
•3. Willingness to attend the CRF on 4-5 occasions and take capsules three times daily for a total period of four weeks
•4. Male & female participants
•5. Aged 18 - 65 years

•1. Age <18 or >65 years old at enrolment
•2. BMI <18 or >45 kg/m2 at enrolment
•3. Pregnancy or breast feeding
•4. Any current medical disorder or history of disorder with potential to influence parameters measured in this study
•5. Any current medical disorder or history of disorder likely to influence the ability follow the study protocol safely and effectively
•6. Any current medication or history of medication likely to influence parameters measured in this study. For example, patients with T2DM should be on oral medication only and not on exogenous insulin or injectable GLP-1 mimetics
•7. Current or historical drug or alcohol abuse
•8. Current smoking habit
•9. Any concern that a potential participant may not understand the nature or requirements of the study sufficiently to consent to participation
•10. Any other circumstance or condition not covered above which would make participation unreasonable

发起方

Cambridge Institute for Medical Research (UK)