NCT00561301Unknown2 期
Biweekly Gemcitabine-Oxaliplatin and Dexamethasone for Relapsed/Refractory Malignant Lymphoma
Cooperative Study Group A for Hematology1 个研究点 分布在 1 个国家目标入组 43 人开始时间: 2006年11月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- objective response rate
研究概览
简要总结
- To evaluate the feasibility of combination chemotherapies comprising of gemcitabine-dexamethasone-oxaliplatin for patients with refractory or relapsed malignant non-Hodgkin lymphoma (NHL)
详细描述
- The feasibility will be evaluated in terms of objective response rate, efficacy of stem cell collection, disease-free survival, and overall survival.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have refractory to first-line CHOP-like regimen
- •Patients who have first relapse after
- •first-line CHOP-like regimen
- •upfront autologous or allogeneic hematopoietic stem cell transplantation
- •Age 15 years or more
- •ECOG performance status ≤ 2
- •Adequate bone marrow function
- •Adequate kidney,liver,cardiac
排除标准
- •Patients who have received GEM or OX
研究组 & 干预措施
1
No Intervention
干预措施: GemDOx (Drug)
结局指标
主要结局
objective response rate
时间窗: 10/2009
次要结局
- toxicities, progression-free survival, overall survival, ASCC efficacy, rate for proceeding to ASCT(10/2009)
研究者
研究点 (1)
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