A randomised controlled trial on prevention of colonization of Staphylococcus aureus in neonates using multiple Bifidobacteria
Not Applicable
- Conditions
- Prevention of colonization of S. aureus
- Registration Number
- JPRN-UMIN000033114
- Lead Sponsor
- Chiba University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1) Neonate whose birth weight is 2000g or more. 2) Infants with a surgical disease (esophageal atresia, diaphragmatic hernia, etc.), long-term enteral nutrition / oral medication administration can not be expected. 3) Neonate who judged to be ineligible by research facility director or research doctor.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Colonization rate of S. aureus in specimens collected in feces, pharynx (nasal culture) up to 4 weeks after birth in each group.
- Secondary Outcome Measures
Name Time Method Measurement of the numbers of three strains Bifidobacterium and Staphylococcus aureus in each group in feces collected at 1 week, 2 weeks and 4 weeks after birth. Difference between the age of each group and birth weight reversion Correlation between weight gain rate and each group at week 40 weeks in preterm infants