NCT00000442已完成4 期
Etiology and Treatment of Alcohol Dependence
UConn Health2 个研究点 分布在 1 个国家目标入组 57 人开始时间: 1999年11月3日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 57
- 试验地点
- 2
研究概览
简要总结
This study is to evaluate the safety and effectiveness of an injectable slow releasing preparation of naltrexone to reduce alcohol consumption and risk of relapse in alcohol-dependent subjects. Individuals will receive either naltrexone or a placebo injection for a total of three months, with two subsequent followup visits spanning a 6- month period.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 主要目的
- Treatment
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meets criteria for alcohol dependence.
- •Abstinent from alcohol for a period of at least 3 days prior to beginning of study.
- •Able to read English and complete study evaluations.
- •Females who are postmenopausal, have had surgical sterilization, or use reliable means of birth control.
排除标准
- •Meets criteria for dependence on a psychoactive substance other than alcohol and nicotine and/or cannabis.
- •Prior history of opioid dependence.
- •Regular use of psychoactive drugs including anxiolytics and antidepressants.
- •Prior treatment with naltrexone.
- •Current use of disulfiram.
- •Psychotic or otherwise severely psychiatrically disabled (e.g., suicidal, current mania).
- •Significant underlying medical conditions such as hepatic, cerebral, renal, thyroid, or cardiac disease.
- •Abstinent longer than 28 days prior to randomization.
研究者
研究点 (2)
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