A Randomized Comparative Clinical Study To evaluate the effect of Patolashunti Ghrita and Jeerakadya ghrita in the management of Urdhwaga Amlapitta with special reference to Dyspepsia.

Amlapitta is one of the most prevalent diseases in the modren era as a result of changing lifestyle,dietary preference and individualbodily constitutions pitta becomes more aggravated especially in its drava and amla characteristics which results in Amlapitta.

Amlapitta is a diseases of *Annavaha srotas ,*caused by vitiation of *Agni,*it is a condition where pitta is accumulated previously from the self aggravating causes gets vidagdha due to virudda,dushta,Amla,Vidahi,Pittakara ahara and Drava like Phanita,Kulatta,Brishta dhanya,Pulaka etc are the primary causes of the disease.Amlapittta has symptoms like Avipaka,Klama,Utklesha,Tikta amlodgara,gourava,Hrut-kanta daha,Aruchi.

It is a pitta pradhana vyadhi where Drava and Amla guna of pachaka pitta are increases,The Dravatavriddi of pitta reduces tikshnata of pachaka pitta as well as vitiates kledaka kapha leading to *Agnimandya.*Thus even little quantity food also not properly digested.

Urdhwaga Amlapitta can be correlated with dyspepsisa with similar clinical presentations.Its symptoms are like sour-bitter bleching,Heart burn,Nausea,Vomiting, Indigestion,Post prandial fullness..

The worldwide prevalence rate of dyspepsia is 20 -30%.It is slightly higher in western population.While the precise prevalence of dyspepsia in India is not Available. Different studies estimate that it affects 7.6-49% of Indian population.

Treatment modalities includes administration of Proton pump inhibitors ,H2 Blockers and Antacids prolong use of these medication cause Nausea,Constipation,Loss of appetite,Stomach ach ,Osteoporosis.

In Ayurveda classics various therapies like Vamana,Virechana,Snehapana,Shamana and Rasayana have been mentioned.Nidana parivarjana ,Amapachana,Agnideepana are the main goals of the Amlapitta treatment.If this diseases not properly treated it may give various comlications in our body like Jwara,Pandu,Shotha ,bhrama.

Jeerakadya Ghrita is mentioned in Bharata Bhaishajya Ratnakara,Amlapitta chikitsa.It contains ingredients like jeeraka ,dhanayaka,and goghrita.Jeeraka has properties like katu,rasa,laghu-ruksha guna,Ushna virya,katu vipaka which helps in Agnideepana and Amapachana.Dhanyaka has properties like kashaya tikta rasa,snigdha guna,ushna virya,Madhura vipaka which help in Agnideepana,Amapachana,dahapnashamana and Pittashamana.

Patola Shunti Ghrita mentioned in *Bhaishajya Ratnavali, Amlapitta chikitsa Adhyaya,*It contains ingredients like Patola,Shunti,Gogrita.Patola has properties like Tikta katu rasa,laghu-ruksha guna,Ushna virya,Katu vipaka.

Shunti has properties Katu rasa,Tikshna guna,Ushna virya,Madhura vipaka.Ghrita has properties like Guru-snigdha guna,Madhura rasa,and Madhura vipaka,Sheeta virya,it acts as Pitta shamaka. due to Teekshna guna it does Shodana.Tikta katu rasa has Vayu and Akasha mahabutha which dries up the Dravata Vriddi of pitta and removes Srotorodha.Katu vipaka helps in Kapha shamaka,Madhura vipaka helps in *Vata pitta Shamaka,*due to Madhura rasa it helps in Dahaprashamana and Pitta shamaka by these properties Patola Shunti Ghrita may in help in samprapti vighatana of Amlapitta.Hence present study will be aimed to evaluate and compare the effect of Patola Shunti Ghrita and Jeerakadya ghrita in *Urdhwaga Amlpapitta (*Dyspepsia).