Time Lapse Imaging Trial

Not Applicable

Completed

• Conditions: In vitro fertilization; Pregnancy and Childbirth

• Registration Number: ISRCTN17792989
• Lead Sponsor: Queen Mary University of London

Brief Summary

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32611445/ protocol (added 05/07/2020) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39033010/ (added 22/07/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-18
• Study Completion: 2023-09-30
• Last Update Posted: 5 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1575

Inclusion Criteria

The inclusion criteria are broad in keeping with the latest NICE guidelines (2013) for NHS funded IVF/ICSI treatment.
Participants undergoing IVF/ICSI treatment and:
1. The woman is between 18 and 42 years of age at the time of consent
2. The male partner is at least 18 years of age at the time of consent
3. Receiving the first, second or third IVF/ICSI treatment cycle
4. Both partners give written informed consent
5. Those having at least 3 2PN embryos (showing 2 pro-nucleii which is a sign of normal fertilisation) on day of fertilization check

Exclusion Criteria

Current exclusion criteria as of 06/04/2020:
1. Participants concomitantly participating in other interventional trials
2. IVF/ICSI treatment using donor gametes
3. Planned pre-implantation genetic diagnostics or screening (PGS/PGD)

Previous exclusion criteria:
1. Participants who have been randomised previously to this trial
2. Participants concomitantly participating in other trials
3. IVF/ICSI treatment using donor gametes
4. Planned pre-implantation genetic diagnostics or screening (PGS/PGD)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of live births, taken from medical notes/contacting the participant; Timepoint(s): Delivery