MedPath

BAROSTIM NEO Hypertension Pivotal Trial

Not Applicable
Suspended
Conditions
Uncontrolled Hypertension
Interventions
Device: BAROSTIM NEO System and Medical Management
Registration Number
NCT01679132
Lead Sponsor
CVRx, Inc.
Brief Summary

The purpose of this clinical investigation (NCT01679132) is to assess the long-term safety and efficacy of the BAROSTIM NEO System in subjects currently participating in the BAROSTIM Hypertension Pivotal Trial (G120137).

Detailed Description

The BAROSTIM NEO Hypertension Trial is a prospective, randomized, controlled trial assessing the safety and efficacy of the BAROSTIM NEO System in subjects with resistant hypertension.

All subjects are now in long term follow-up and are required to have at least one annual visit.

Parameters assessed during visits are:

* Office Cuff Blood Pressure

* Physical Assessment

* Subject Medications

* Serious adverse events

Recruitment & Eligibility

Status
SUSPENDED
Sex
All
Target Recruitment
10
Inclusion Criteria
  • Actively participating in the Barostim Hypertension Pivotal Trial and currently implanted with the BAROSTIM NEO device with the device turned ON.
  • Have signed a revised approved informed consent form for continued participation in this study.
Exclusion Criteria
  • Treating physician decision that the subject should not continue with therapy.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
BAROSTIM NEO SystemBAROSTIM NEO System and Medical ManagementSubjects implanted with the BAROSTIM NEO System.
Primary Outcome Measures
NameTimeMethod
To assess long-term adverse events in subjects implanted with the BAROSTIM NEO System.For the duration of the study, up to ten years.

Ascertain the type, frequency, severity and timing of long-term adverse events in G120137 study subjects implanted with the device, while providing a viable treatment option to patients currently implanted with the CVRx BAROSTIM NEO System.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (11)

University of Southern California

🇺🇸

Los Angeles, California, United States

Tampa General Hospital

🇺🇸

Tampa, Florida, United States

Cardiovascular Institute of the South

🇺🇸

Houma, Louisiana, United States

Florida Hospital

🇺🇸

Orlando, Florida, United States

Cardiac and Vascular Research Center of Northern Michigan

🇺🇸

Petoskey, Michigan, United States

George Washington University

🇺🇸

Washington, District of Columbia, United States

University Medical Center of Southern Nevada

🇺🇸

Las Vegas, Nevada, United States

Allegheny General Hospital

🇺🇸

Pittsburgh, Pennsylvania, United States

Aspirus Wausau Hospital

🇺🇸

Wausau, Wisconsin, United States

Arizona Heart Rhythm Research Center

🇺🇸

Phoenix, Arizona, United States

Michigan CardioVascular Institute

🇺🇸

Saginaw, Michigan, United States

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