Effectiveness of Pregabalin and Nortriptyline on neuropathic pain in post-burn injuries

Phase 4

• Conditions: europathic pain.; G89.29; Neuropathi

• Registration Number: IRCT20100501003844N4
• Lead Sponsor: Rasht University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 8 March 2022

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Having an age of 65-18 years
History of 5% or more burns above body level
Have a pain score of 4 or higher (moderate to severe pain) based on the Brief Pain Inventory (BPI-P)
Informed written consent and the ability to confirm in writing the participation in the study
No history of allergy to pregabalin and nortriptyline
Ability to swallow capsules
Not pregnant and communicating with the research team.

Exclusion Criteria

History of consecutive use of any anticonvulsant medication during and after the burn
History of pre-burn neuropathic pain
A specific history of mental illness or substance abuse before and after burns

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score less than 4. Timepoint: In the recovery unit (0 hours) and 24 hours after the procedure, pain intensity is measured in two groups with pain criterion (BPI-P). Method of measurement: In this way, people are asked to show their pain intensity on a 10 cm ruler. no pain will be scored as zero and score 10 is for the highest pain.