Skip to main content
MedPathMedPath Home
Clinical Trials/EUCTR2011-001856-12-CZ
EUCTR2011-001856-12-CZ
Active, not recruiting
Phase 1

Early assessment of effectivness of neoadjuvant chemotherapy for carcinoma of the esophagus and esophago-gastric junction using FDG-PET/CT.

The Motol University Hospital0 sitesJuly 26, 2011
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Not specified
Sponsor
The Motol University Hospital
Status
Active, not recruiting
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 26, 2011
End Date
TBD
Last Updated
9 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
The Motol University Hospital

Eligibility Criteria

Inclusion Criteria

  • •age 18\-75 years, males and females
  • •histologically verified adenocarcinoma of the esophagus or esophago\-gastric junction or proximal stomach affecting cardia
  • •no distant metastases or non\-regional lymph node metastasis on computed tomography of chest and abdomen
  • •cT1, N1, M0\-1a or cT2\-T4 (potentially resectable tumor), N0\-1, M0\-1a (TNM staging AJCC 6th edition) on EUS and CT
  • •performance status 0\-1 (WHO)
  • •medically fit for elective esophagectomy after neoadjuvant chemotherapy
  • •signed informed consent
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes

Exclusion Criteria

  • •Patients with insulin\-dependent diabetes mellitus or DM II on oral antidiabetics with glycemia level above 10 mmol/l
  • •Patients with the finding of distant organ metastases at the inicial FDG\-PET/CT will be excluded from the study
  • •pregnant or nursing women

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Phase 3
Investigating the effect of neoadjuvant chemotherapy on locally advanced rectal cancerocally advanced Rectal cancers.
IRCT20210308050628N1Hamedan University of Medical Sciences300
Completed
Phase 2
Effect of preoperative chemotherapy in the treatment of patients with locally advanced rectal cancerRectal cancer.Malignant neoplasm of rectum
IRCT2016082129403N2Vice chancellor for research, Shiraz University of Medical Sciences40
Not yet recruiting
Phase 2
Combined neoadjuvant chemotherapy docetaxel (Taxotere), cisplatin and 5-Fluorouracil and concurrent chemoradiation in treating patients with locally advanced cancer of the larynxHead and neck cancerlaryngeal cancerCancer - Head and neck
ACTRN12610000856011Shiraz University of Medical Sciences50
Recruiting
Phase 2
Combined neoadjuvant chemotherapy docetaxel (Taxotere), cisplatin and 5-Fluorouracil and concurrent chemoradiation in treating patients with locally advanced nasopharyngeal carcinoma
ACTRN12611000835943Shiraz University of Medical Sciences50
Active, not recruiting
Phase 2
Combined neoadjuvant chemotherapy docetaxel (Taxotere), cisplatin and 5-Fluorouracil and concurrent chemoradiation in treating patients with squamous cell carcinoma of the hypopharynxhypopharyngeal cancerCancer - Head and neck
ACTRN12610000870055Shiraz University of Medical Sciences50