Prognosis of Acute Kidney Injury:China Collaborative Study on AKI(CCS-AKI)Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Kidney Injury
- Sponsor
- XinLing Liang
- Enrollment
- 1000000
- Locations
- 1
- Primary Endpoint
- estimated glomerular filtration rate decline
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
Acute kidney injury (AKI) is a common clinical syndrome, especially in the hospital patients. AKI is recognized as an important risk factor for incident chronic kidney disease, accelerated progression to end-stage renal disease,and increased risk of short-term and long-term mortality.This study is to observe the prognosis of hospitalized patients with AKI in China.
Investigators
XinLing Liang
Director of Division of Nephrology and Blood Purification Center of Guangdong General Hospital
Guangdong Provincial People's Hospital
Eligibility Criteria
Inclusion Criteria
- •clinically diagnosed with acute kidney injury, according to KDIGO criteria
Exclusion Criteria
- •Nephrectomy
- •Kidney transplantation
- •Peak serum creatinine of less than 53µ mol/L
- •Serum creatinine decrease after amputation
- •Patients died during hospitalization
- •End-stage kidney disease(chronic kidney disease stage 5)
- •malnutrition
Outcomes
Primary Outcomes
estimated glomerular filtration rate decline
Time Frame: 2 years
\>50% baseline
New cardiovascular events
Time Frame: 5 years
All-cause mortality
Time Frame: 5 years
Chronic kidney disease classification upgrade
Time Frame: 5 years
Secondary Outcomes
- Rehospitalization(5 years)
- AKI recovery(5 years)