Prognosis of Acute Kidney Injury:China Collaborative Study on AKI（CCS-AKI）Study

Recruiting

• Conditions: Acute Kidney Injury

• Registration Number: NCT03061786
• Lead Sponsor: XinLing Liang

Brief Summary

Acute kidney injury (AKI) is a common clinical syndrome, especially in the hospital patients. AKI is recognized as an important risk factor for incident chronic kidney disease, accelerated progression to end-stage renal disease,and increased risk of short-term and long-term mortality.This study is to observe the prognosis of hospitalized patients with AKI in China.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-01
• Study First Submitted: 2017-02-15
• Study First Submitted QC: 2017-02-19
• Study First Posted: 2017-02-23
• Status Verified: 2022-12
• Last Update Submitted: 2022-12-10
• Last Update Posted: 2022-12-13
• Primary Completion: 2027-12
• Study Completion: 2027-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000000

Inclusion Criteria

• clinically diagnosed with acute kidney injury, according to KDIGO criteria

Exclusion Criteria

• Nephrectomy
• Kidney transplantation
• Peak serum creatinine of less than 53µ mol/L
• Serum creatinine decrease after amputation
• Patients died during hospitalization
• End-stage kidney disease(chronic kidney disease stage 5)
• malnutrition

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
estimated glomerular filtration rate decline	2 years	\>50% baseline
New cardiovascular events	5 years
All-cause mortality	5 years
Chronic kidney disease classification upgrade	5 years

Secondary Outcome Measures

Name	Time	Method
Rehospitalization	5 years
AKI recovery	5 years

Trial Locations

Locations (1)

Guangdong General Hospital; 🇨🇳 Guangzhou, Guangdong, China