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Clinical Trials/NCT06240325
NCT06240325
Recruiting
N/A

A Sleep Promotion Program for Depressed Adolescents in Pediatric Primary Care

University of Pittsburgh1 site in 1 country100 target enrollmentDecember 13, 2024

Overview

Phase
N/A
Intervention
SPP
Conditions
Sleep
Sponsor
University of Pittsburgh
Enrollment
100
Locations
1
Primary Endpoint
Feasibility of Intervention Measure
Status
Recruiting
Last Updated
last month

Overview

Brief Summary

Investigators developed a brief, scalable, behavioral Sleep Promotion Program (SPP) for adolescents with short sleep duration and sleep-wake irregularity, which relies on two individual sessions and smart phone technology to deliver evidence-based strategies. This R34 will test the feasibility and initial effectiveness of the SPP program and provider training via pilot randomized controlled trial (RCT, n=50) comparing SPP to Sleep Psychoeducation, a brief session on healthy sleep habits. Participants will be adolescents (12-18 years) with short sleep duration, sleep-wake irregularity, and depression.

Registry
clinicaltrials.gov
Start Date
December 13, 2024
End Date
August 1, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jessica Levenson

Assistant Professor

University of Pittsburgh

Eligibility Criteria

Inclusion Criteria

  • Able and willing to provide informed assent (with consent from parent/guardian)
  • Ages 12-18
  • Currently a patient at Kids Plus Pediatrics
  • Currently depressed
  • Report short sleep duration (\<7 hours on school nights) and/or weekday-weekend sleep timing difference of \>=2 hours
  • Parents must be age 18 or older and the parent/guardian of an enrolled youth participant and must have at least 10 hours face-to-face interaction with the youth participant per week.

Exclusion Criteria

  • Significant or unstable medical conditions
  • Diagnosis of sleep apnea, narcolepsy, restless leg syndrome, nightmare disorder, or periodic limb movement disorder
  • Diagnosis of PTSD, bipolar disorder, a psychotic disorder, or substance use disorder
  • Currently engaged in cognitive and/or behavioral therapy that aims to improve sleep
  • Changes in medications in the month prior to screening
  • Active suicidality requiring immediate treatment
  • Unable or unwilling to comply with study procedures
  • Have any physical or mental condition that would preclude study participation.
  • Parents will be excluded if they:
  • Express active suicidality that requires immediate treatment;

Arms & Interventions

Sleep Promotion Program

Participants will receive the Sleep Promotion Program (SPP), consisting of 2 individual sessions with a clinician via telehealth (or in-person if desired), about 2 weeks apart, and web-based intervention components.

Intervention: SPP

Sleep Psychoeducation

Participants will receive Sleep Psychoeducation (SPE), a 20-minute discussion with a clinician via telehealth (or in person).

Intervention: Sleep Psychoeducation

Outcomes

Primary Outcomes

Feasibility of Intervention Measure

Time Frame: Post-Intervention (~8 weeks)

The Feasibility of Intervention Measure (FIM) is a 4-item measure that assesses the feasibility of the intervention, each item is scored on a 1-5 likert scale (completely disagree to completely agree). Items can be evaluated individually or a scale can be created by averaging responses. Scale values range from 1-5.

Clinical Global Impressions Scale - Improvement

Time Frame: Post-Intervention (~8 weeks)

This is a clinician rating of improvement in sleep and psychopathology. Clinicians rate domains of sleep health, psychiatric symptoms, and overall health on a range from 1 very much improved) to 7 (very much worse). A score of 0 indicates no assessment. Scores for each domain are reported individually.

Acceptability of Intervention Measure

Time Frame: Post-Intervention (~8 weeks)

The Acceptability of Intervention Measure (AIM) is a 4-item measure that assesses the acceptability of the intervention, each item is scored on a 1-5 likert scale (completely disagree to completely agree). Items can be evaluated individually or a scale can be created by averaging responses. Scale values range from 1-5.

Intervention Appropriateness Measure

Time Frame: Post-Intervention (~8 weeks)

The Intervention Appropriateness Measure (IAM) is a 4-item measure that assesses the appropriateness of the intervention, each item is scored on a 1-5 likert scale (completely disagree to completely agree). Items can be evaluated individually or a scale can be created by averaging responses. Scale values range from 1-5.

Patient Health Questionnaire - 9 - M

Time Frame: Change Screening to Post-Intervention (~10 weeks)

This is a self-report measure of depressive symptoms. It consists of 9 items rated 0 (not at all) to 3 (nearly every day) over the past 2 weeks. Scores on those 9 items are summed to create a total score (0-27, higher score indicates greater depression).

Secondary Outcomes

  • Sleep Diary Sleep Duration(Baseline to Post-Intervention (~8 weeks))
  • Pediatric Sleep Survey PC(Training Start to End of Study Involvement (up to 2.5 years))
  • Pediatric Sleep Survey Sleep Knowledge (SK)(Training Start to End of Study Involvement (Up to 2.5 years))
  • SPP Therapy Rating Scale(Completed at each SPP Session (2 and 4 weeks after baseline))
  • Sleep Diary Sleep-Wake Regularity(Baseline to Post-Intervention (~8 weeks))
  • Quick Inventory of Depressive Symptoms - Adolescent (17 item) - Self-Report (QIDS-A17-SR)(Baseline to Post-Intervention (~8 weeks))

Study Sites (1)

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