Comparing spinal anesthesia given in one single bolus dose versus given in fractionated dose ie two third dose given initially followed by one-third dose and compare their efficacy

Not Applicable

• Conditions: Health Condition 1: O- Medical and Surgical

• Registration Number: CTRI/2021/09/036166
• Lead Sponsor: SRUTHI S MATHAI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All patients undergoing lower limb surgeries with american society of anaesthesiologist physical status 1 and 2

-BMI of 18.5 -24.9kg/m2

- Height of1 50-180cm

Exclusion Criteria

1.American Society of Anesthesiologists (ASA) physical status 3 and 4.

2.Patients with pre-existing cardiovascular or cerebrovascular disease.

3.Patients with known allergy or hypersensitivity to local anesthetic drugs.

4.Patients with deformities of spine and history of laminectomy

5.Contraindications to Regional anesthesia (including coagulopathy and local infection).

6.Patients with inadequate sensory blockade and requiring conversion to general anesthesia.

7.Patients with increased intracranial pressure and altered mental status.

8.BMI of less than 18.5 kg/m2 or more than 22.9kg/m2.

9. Height less than 150cm or more than 180cm.

10.Patient not willing to give consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare both fractionated and bolus dose and evaluate which has better analgesia in post operative period, better hemodynamic stability and better sensory and motor blockwith respect to the following parameters: <br/ ><br>1. heart rate <br/ ><br>2. systolic BP <br/ ><br>3. Diastolic BP <br/ ><br>4.Mean arterial pressure <br/ ><br>5. saturation. <br/ ><br>6. Time for first rescue analgesics.Timepoint: Patient will be assessed every 2 mins in the first 30 mins and every 5 mins till the end of surgery for the following parameters: <br/ ><br>1. BP <br/ ><br>2. HEART RATE <br/ ><br>3. SATURATION.

Secondary Outcome Measures

Name	Time	Method
Time needed for rescue analgesiaTimepoint: The time taken forthe first analgesia to be given will be noted .