Skip to main content
Clinical Trials/NCT05261061
NCT05261061
Unknown
Not Applicable

Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19

Assistance Publique - Hôpitaux de Paris1 site in 1 country1,000 target enrollmentJuly 2022
ConditionsCOVID-19

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COVID-19
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
1000
Locations
1
Primary Endpoint
One-year mortality
Last Updated
3 years ago

Overview

Brief Summary

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age, frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy. Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors).

For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Detailed Description

Old patients hospitalized in Acute Geriatric Units are characterize by advanced age (average 85 years), frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy.These particular state leads to multiple decompensations and the reason for initial hospitalization is often only the "tip of the iceberg". Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors). For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). This excess mortality is all the more surprising as these patients seem to have fewer comorbidities than those usually hospitalized in acute geriatric units. Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.

Registry
clinicaltrials.gov
Start Date
July 2022
End Date
December 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age \>=75 years
  • Hospitalized for medical reason in acute geriatric unit
  • Alive at hospital discharge

Exclusion Criteria

  • Patients hospitalized for surgical reason
  • Patients under legal protection
  • Patient refusal

Outcomes

Primary Outcomes

One-year mortality

Time Frame: 1 year

Secondary Outcomes

  • SF-12 at one year(1 year)
  • Clinical Frailty Scale (CFS) at one year(1 year)
  • rehospitalization at one year(1 year)
  • Activity of daily living (ADL) at 1 year(1 year)

Study Sites (1)

Loading locations...

Similar Trials