Prognosis of Geriatric Patients 1 Year After Hospitalization for COVID-19
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19
- Sponsor
- Assistance Publique - Hôpitaux de Paris
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- One-year mortality
- Last Updated
- 3 years ago
Overview
Brief Summary
Old patients hospitalized in Acute Geriatric Units are characterize by advanced age, frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy. Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors).
For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.
Detailed Description
Old patients hospitalized in Acute Geriatric Units are characterize by advanced age (average 85 years), frailty, high number of comorbidities, cognitive impairment and loss of functional autonomy.These particular state leads to multiple decompensations and the reason for initial hospitalization is often only the "tip of the iceberg". Although, intra-hospital mortality in geriatric population (out of COVID) is low (6%) the long-term prognosis is often worse (30 to 60% of loss of autonomy and 30% of one-year mortality among hospital survivors). For geriatric patients with COVID19, intra-hospital mortality is higher than in younger Covid patients (1), but also higher than in geriatric patients outside the Covid context (30 vs 6% (2, 3)). This excess mortality is all the more surprising as these patients seem to have fewer comorbidities than those usually hospitalized in acute geriatric units. Our hypothesis is that geriatric patients surviving hospitalization for COVID-19 have a worse vital and functional prognosis at 12 months than geriatric patients surviving hospitalization for another medical reason.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \>=75 years
- •Hospitalized for medical reason in acute geriatric unit
- •Alive at hospital discharge
Exclusion Criteria
- •Patients hospitalized for surgical reason
- •Patients under legal protection
- •Patient refusal
Outcomes
Primary Outcomes
One-year mortality
Time Frame: 1 year
Secondary Outcomes
- SF-12 at one year(1 year)
- Clinical Frailty Scale (CFS) at one year(1 year)
- rehospitalization at one year(1 year)
- Activity of daily living (ADL) at 1 year(1 year)