NCT05065567终止3 期
A Comparison of Haloperidol 5mg IM vs Droperidol 2.5mg and Ondansetron for the Treatment of Hyperemesis in Cannabis Hyperemesis Syndrome
Spectrum Health - Lakeland1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2021年8月30日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 终止
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Abdominal Pain
研究概览
简要总结
The purpose of this study is to compare two commonly used agents for the treatment of cyclic vomiting to see if one agent is inferior to the other in time to improvement in symptoms, need for repeat or rescue medications, treatment failures and complications/side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients with clinical diagnosis of cyclic vomiting in the ED
排除标准
- •pregnancy, allergy to any of the study medicines
研究组 & 干预措施
haloperidol
Active Comparator
these patients will receive 5mg IM haloperidol
干预措施: Haloperidol (Drug)
droperidol
Active Comparator
these patients will receive 2.5mg IV droperidol
干预措施: Droperidol (Drug)
ondansetron
Active Comparator
these patients will receive 8mg IV ondansetron
干预措施: Ondansetron 8mg (Drug)
结局指标
主要结局
Abdominal Pain
时间窗: 48 hours
change in abdominal pain on 0 (no pain) through 10 (worse possible pain) on a visual analog scale
Nausea
时间窗: 48 hours
change in nausea on 0 (none) through 10 (worse possible nausea) on a scale
次要结局
- Treatment Success(48 hours)
研究者
研究点 (1)
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