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临床试验/NCT02752893
NCT02752893已完成不适用

Estrogen Receptor-Positive Breast Cancer Patient-Derived Xenografts

Dartmouth-Hitchcock Medical Center1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2017年1月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
1
主要终点
Xenograft success rate, defined as the percentage of patient tumors that yield a growing xenograft in mice.

研究概览

简要总结

The investigators will establish a platform at Dartmouth-Hitchcock Medical Center to generate novel models of estrogen receptor alpha-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer, which will be used for research studies to develop novel treatment strategies and dissect signaling pathways underlying drug sensitivity and resistance.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Xenograft success rate, defined as the percentage of patient tumors that yield a growing xenograft in mice.

时间窗: 1 year from time of surgery

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gary Schwartz

Staff Physician, Hematology-Oncology

Dartmouth-Hitchcock Medical Center

研究点 (1)

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