Regeneration of Intrabony Defects With Nano Hydroxyapatite Graft, Derived From Egg Shell Along With Periosteum as Barrier Membrane Under Magnification - An Interventional Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Bone defect fill and density
研究概览
简要总结
The prospective study is a interventional study to evaluate and compare the effectiveness of periosteal pedicle as grafting technique and egg shell derived nano hydroxyapatite as regenerative graft material for regeneration of intrabony defects.
详细描述
30 Patients visiting the outpatient Department of Periodontology Krishnadevaraya College of Dental Sciences and Hospital, Bangalore will be enrolled for 6 month folllow up study based on the inclusion and exclusion criteria. Patients age ranged from 25 to 55 years. Patients with chronic periodontitis, with presence of intrabony defects with ≥6mm probing depth (PD), 2 or 3 wall defects are included in the study.
The patients are allocated to three goups through computer generated randomisation as:
Group A (n=10) - Egg shell derived nano hydroxyapatite (EnHA) graft and periosteal pedicle as barrier membrane.
Group B (n=10) - Only EnHA as graft. Group C (n=10) - An open flap debridement procedure only.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients within the age group of 25 to 55 years.
- •Patients with chronic periodontitis, with presence of intrabony defects with ≥6mm probing depth (PD), 2 or 3 wall defects as detected on CBCT.
- •Gingival biotype >1.5mm
- •Systemically healthy subjects.
- •Patients who are compliant.
- •Patients who had not received any periodontal treatment in the last six months.
排除标准
- •Pregnant and Lactating females.
- •Aggressive periodontitis.
- •Presence of pulpal or periapical involvement.
- •Patients with known systemic diseases and conditions precluding any elective surgery.
- •Patients who were smokers.
- •Teeth with poor prognosis.
结局指标
主要结局
Bone defect fill and density
时间窗: 6 months
bone defect fill and bone density will be measured pre operatively and post operatively using CBCT
次要结局
- Probing pocket depth(6 months)
研究者
Dr Prabhuji MLV
Professor and HOD
Krishnadevaraya College of Dental Sciences & Hospital