Duration of luteal phase support with progesterone pessaries to improve the success rate in assisted reproduction cycles. A prospective randomised control trial. - DOLS
Phase 1
- Conditions
- Women undergoing assisted conception
- Registration Number
- EUCTR2006-000599-33-GB
- Lead Sponsor
- iverpool Women's NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 460
Inclusion Criteria
Biochemical pregnancy 2 weeks after embryo transfer using a urinary pregnancy test.
Progesterone treatment (2 weeks) completed upto day of pregnancy test.
Fresh embryo IVF/ICSI cycle.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Frozen embryo transfer
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To determine if an extra 10 weeks of progesterone (to make 12 weeks), after embryo implantation, increases the successful clinical pregnancy rate in assisted conception;Secondary Objective: ;<br> Primary end point(s): Viable pregnancy at 14 weeks on ultrasound scan. (At end of period taking pessaries).<br> Live birth.<br>
- Secondary Outcome Measures
Name Time Method