JPRN-UMIN000023082已完成未知
Clinical significance of diffusion MRI in patients with moyamoya disease - diffusion MRI of moyamoya disease
Tokyo Medical and Dental University, Department of Neurosurgery0 个研究点目标入组 31 人开始时间: 2016年7月12日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 31
研究概览
简要总结
This study revealed that patients with moyamoya disease suffer from chronic ischemic damage to the brain microstructure, i.e. decreased neurite density and simplified network complexity, and the degree of ischemic damage is related to neurocognitive dysfunction and the degree of hemodynamic and metabolic dysfunction. We also found that diffusion magnetic resonance imaging might be used to noninvasevely evaluate cerebral hemodynamic impairment in patients with moyamoya disease.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6years-old 至 65years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. patients with quasi-moyamoya disease 2. contraindication of MRI examination 3. brain lesion other than moyamoya disease affecting MRI parameters (e.g. brain tumor, venous angioma) 4. judged as inappropriate participants by doctor-in-charge
研究者
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